Curriculum Vitae - Khan
Board Status:
Board Eligible by the American Board of Neurological Surgeons
2020 Primary Written Examination, Oral anticipated Fall 2026
Employment:
Neurosurgeon, Neurosurgical Medical Clinic, Inc, San Diego, CA, 03/2026- current
Director, Skull Base Neurosurgery, Intnet Medical Group, North Short University (Endeavor Healthcare), Arlington Heights, IL, 07/2024 – 02/2026
Education:
Pacific Neuroscience Institute, Santa Monica, California, 07/2023 - 06/2024
Fellowship: Minimally Invasive Neurological Surgery
Mentors: Daniel Kelly, MD and Garni Barkhoudarian, MD
University of California, San Diego, San Diego, California, 07/2016 – 06/2023
Residency: Neurological Surgery
University of Arizona, Banner-University Medical Center, Phoenix, Arizona, 01/2022 – 06/2022
Fellowship: Cerebrovascular and Skull Base Neurosurgery
Mentor: Peter Nakaji, MD
Kavli Institute, University of California, San Diego, La Jolla, California, 07/2019 – 06/2020
Post-Doctoral Fellow Systems Neuroscience
Advisors: Jill and Stefan Leutgeb, PhD
State University of New York, Brooklyn, New York, 09/2008 – 05/2016
MD, PhD Neural and Behavioral Sciences
Dissertation: Imaging the Hippocampal Formation in Alzheimer’s Disease
Thesis Advisors: Scott Small, MD- Columbia University College of Physicians and Surgeons
Herman Moreno, MD- State University of New York
University of Rochester, Rochester, New York, 08/2005
BS - Neuroscience
Awards:
James S McDonnell Foundation Fellowship, 2012 – 2013
Mapping Dentate Gyrus Cerebral Blood Volume Using Automated Imaging Tools
James S McDonnell Foundation Fellowship, 2013 – 2014
Optimizing New Imaging Tools to Fully Map Hippocampal Formation Cerebral Blood Volume
Publications and Papers:
1) Khan UA, Plonsker J, Levy ML, Friedman RA, Schwartz MS. Real World Application of a Generalist ArtificialIntelligence in Neurosurgical Practice. New England Journal of Medicine: AI. In Review
2) Khan UA, Ren Y, Vahabzadeh-Hagh AM, Friedman RF, Schwartz MS. Retrolabyrinthine Infratemporal Fossa Trans- Sigmoid Approach for the Resection of a Large Lower Cranial Nerve Schwannoma with Ansa Cervicalis-Recurrent Laryngeal Nerve Anastomosis. 2-Dimensional Operative Video. Operative Neurosurgery. In Review
3) de Cos V, Gibson M, Li V, La Monte O, Moshtaghi O, Dixon PR, Khan UA, Friedman RA, Schwartz MS. Audiometric Outcomes of Auditory Brainstem Implantation During Vestibular Schwannoma Resection in NF2 Patients. Journal of Neurological Surgery Part B: Skull Base, vol. 85, no. 2, 2024, pp. 145-155. DOI: 10.1055/a-2236-0113.
4) Brandel MG, Plonsker JH, Khan UA, Rennert RC, Friedman RA, Schwartz MS. Going The Distance In Acoustic Neuroma Resection: Microsurgical Outcomes At High-Volume Centers of Excellence. J Neurooncol 163, 105–114 (2023).
5) Dixon PR, Moshtaghi O, Khan UA, Harris JP, Schwartz MS, Friedman RA. Association Between Facility Surgical Volume and Excess Time in the Hospital After Surgical Resection of Vestibular Schwannomas. JAMA Otolaryngology Head Neck Surg. 2023 Mar 2:e225243
Featured In: Stewart, C. M. Discharge After Vestibular Schwannoma Surgery-How to Draw the Line for Hospital Volume and Timeliness. JAMA Otolaryngology--Head & Neck Surgery (2023).
6) Dixon P, Wojdyla L, Lee J, Moshtaghi O, Claussen A, Khan UA, McDonald M, Schwartz M, Friedman R. (2022). Machine Learning to Predict Hearing Preservation After Middle Cranial Fossa Approach for Sporadic Vestibular Schwannomas. Otology & Neurotology, 43 (9), 1072-1077
7) La Monte OA.; Tawfik KO.; Khan UA; Schwartz M; Friedman R. Analysis of Hearing Preservation in Middle Cranial Fossa Resection of Vestibular Schwannoma. Otology & Neurotology 43(3):p 395-399, March 2022.
8) Khan UA, Plonsker JH, Friedman RA, Schwartz MS. Combined translabyrinthine, anterior petrosal approach for resection of collision vestibular schwannoma and petrous apex meningioma in neurofibromatosis type 2, with auditory brainstem implant placement. Neurosurgical Focus Video. 2021 Oct 1;5(2):V17
9) Metastatic epidural spinal column compression due to pancreatic ductal adenocarcinoma causing subacute Cauda equina syndrome: A case report. Diaz-Aguilar L, Khan UA, Sahyouni R, Brown NJ, Olson S, Osorio JA. Surg Neurol Int. 2020 Sep 5;11:279
10) Combined Petrosal Approach for Resection of Collision Sphenopetroclival Meningioma and Vestibular Schwannoma in Neurofibromatosis- Type Two with Auditory Brainstem Implant. 2-Dimensional Operative Video. Khan UA, Ren Y, Friedman RF, Schwartz MS Neurosurgical Focus Video. 2021 Oct; 5(2): V17
11) Hearing Preservation in Middle Cranial Fossa Resection of Vestibular Schwannoma. LaMonte O, Tawfik KO, Khan UA, Friedman RF Otology & Neurotology 43(3):p 395-399
12) Treatment of Small Vestibular Schwannomas. Tawfik KO, Khan UA, Friedman RA. Current OtorhinolaryngologyReports volume 9, pages 139–154
13) Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial. Salman RA, RESTART Collaboration, et al. The Lancet (18:7) 643-652 393(10191) 2613-2623.
14) Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial. Salman RA, RESTART Collaboration, et al. The Lancet: Neurology (18:7) 643-652
15) Rennert RC, Khan U, Bartek J, Tatter SB, Field M, Toyota B, Fecci PE, Judy K, Mohammadi AM, Landazuri P, Sloan AE, Kim AH, Leuthardt EC, Chen CC. Laser Ablation of Abnormal Neurological Tissue Using Robotic Neuroblate System (LAANTERN): Procedural Safety and Hospitalization. Neurosurgery. 2019 May 11. pii: nyz141
16) Lander SS, Khan U, Lewandowski N, Chakraborty D, Provenzano FA, Mingote S, Chornyy S, Frigerio F, Maechler P, Kaphzan H, Small SA, Rayport S, Gaisler-Salomon I. Glutamate Dehydrogenase-Deficient Mice Display Schizophrenia-Like Behavioral Abnormalities and CA1-Specific Hippocampal Dysfunction. Schizophrenia Bulletin. 2019 Jan 1;45(1):127-137
17) Rennert RC, Khan U, Tatter SB, Field M, Toyota B, Fecci PE, Judy K, Mohammadi AM, Landazuri P, Sloan A, Leuthardt E, Chen CC. Patterns of Clinical Use of Stereotactic Laser Ablation: Analysis of a Multicenter Prospective Registry. World Neurosurg. 2018 Aug;116: e566-e570
18) Khan UA, Rennert RC, White NS, Bartsch H, Farid N, Dale AM, Chen CC. Diagnostic utility of restriction spectrum imaging (RSI) in glioblastoma patients after concurrent radiation-temozolomide treatment: A pilot study. J Clin Neurosci. 2018 Dec; 58:136-141
19) Nuriel T, Angulo SL, Khan U, Ashok A, Chen Q, Figueroa HY, Emrani S, Liu L, Herman M, Barrett G, Savage V, Buitrago L, Cepeda-Prado E, Fung C, Goldberg E, Gross SS, Hussaini SA, Moreno H, Small SA, Duff KE. Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer’s disease-like pathology. Nature Communications; 2017; 8, 1464
20) Nuriel T, Khan U, Angulo SL, Ashok A, Gross SS, Hussaini SA, Moreno H, Small SA, Duff KE. ApoE4 Induces Entorhinal Cortex Hypermetabolism In the Absence of Overt Alzheimer’s Disease Pathology. June 2017, Alzheimer's and Dementia 13(7): P204
21) Chen CC, Rennert R, Khan UA, Tatter SB, Field M, Toyota B, Fecci PE, Judy KD, Mohammadi AM, Landazuri P. 372 Evolving Patterns in Clinical Utilization of Stereotactic Laser Ablation (SLA): An Analysis of the Multi-center Prospective Registry LAANTERN. Neurosurgery, Volume 64, Sep 2017
22) Chen CC, Rennert R, Khan UA, Tatter SB, Field M, Toyota B, Fecci PE, Judy KD, Mohammadi AM, Landazuri P, Sloan AE, Leuthardt EC. 223 Procedural Safety of Stereotactic Laser Ablation (SLA) and Associated Hospital Stay: Outcome from the First Hundred Patient from LAANTERN Prospective Registry. Neurosurgery, Volume 64. 2017
23) Gabel BC, Cleary DR, Martin JR, Khan UA, Snyder V, U HS. Unusual and Rare Locations for Craniopharyngiomas: Clinical Significance and Review of the Literature. World Neurosurgery, 2017, 98 (381-387)
24) Wöhr M, Orduz D, Gregory P, Moreno H, Khan U, Vörckel KJ, Wolfer DP, Welzl H, Gall D, Schiffmann SN, Schwaller B. Lack of parvalbumin in mice leads to behavioral deficits relevant to all human autism core symptoms and related neural morphofunctional abnormalities. Translational Psychiatry 2015; 5: e525
25) Brickman AM, Khan UA, Provenzano FA, Yeung LK, Suzuki W, Schroeter H, Wall M, Sloan RP, Small SA. Enhancing
dentate gyrus function with dietary flavanols improves cognition in older adults. Nature Neuroscience 2014; 17(12): 1798-1803. Featured in: Pa J, Gazzaley A. Flavanol-rich food for thought. Nature Neuroscience 2014; 17(12): 1624-1625 Belluck P. "To Improve a Memory, Consider Chocolate." The New York Times. 10-26- 2014.
26) Khan UA, Liu L, Provenzano FA, Berman DE, Profaci CP, Sloan R, Mayeux R, Duff KE, Small SA. Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease. Nature Neuroscience 2014; 17(2):304-311.
Featured in: Yassa MA. Ground Zero in Alzheimer’s Disease. Nature Neuroscience; 17(2);146- 147.
27) Lewandowski NM, Bordelon Y, Brickman AM, Angulo S, Khan UA, Muraskin J, Griffith EY, Wasserman P, Menalled L, Vonsattel JP, Marder K, Small SA, Moreno H. Regional vulnerability in Huntington's disease: fMRI-guided molecular analysis in patients and a mouse model of disease. Neurobiology of Disease 2013; 52(1):84-93
28) Schober SA, *Chaudhury NH, Khan UA, Paniagua B, Styner MA, Asllani I, Inbar BP, Corcoran CM, Lieberman JA, Moore H, Small SA. Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver. Neuron 2013; 78(1):81-93 Featured in: A Mechanistic Approach to Preventing Schizophrenia in At-Risk Individuals. Neuron 2013; 78(1):1-3
29) Cepeda-Prado E, Popp S, Khan UA, Stefanov D, Rodríguez J, Menalled LB, Dow-Edwards D, Small SA, Moreno H. R6/2 Huntington's disease mice develop early and progressive abnormal brain metabolism and seizures. The Journal of Neuroscience 2012; 32(19):6456-6467.
30) Whitford TJ, Kubicki M, Schneiderman JS, O'Donnell L, King R, Alvarado JL, Khan UA, Markant D, Nestor PG, Niznikiewicz M, McCarley RW, Westin C-F, Shenton ME. Corpus callosum abnormalities and their association with psychotic symptoms in patients with schizophrenia. Biological Psychiatry 2010;68(1):70-77. Cover Article
Invited Seminars, Lectures, Oral Presentations:
1) Hearing Preservation in Middle Cranial Fossa Resection of Vestibular Schwannoma. LaMonte O, Tawfik KO, Khan UA, Friedman RF American Neurotology Society, 2020
2) Neuromodulation of Memory and Memory Loss. Annual Resident Research Conference, UC San Diego. 2020
3) Chen CC, Rennert R, Khan U, Tatter SB, Field M, Toyota B, Fecci PE, Judy KD, Mohammadi AM, Landazuri P, Sloan,AE, Leuthardt EC. Evolving Patterns in Clinical Utilization of Stereotactic Laser Ablation (SLA): An Analysis of The Multi-Center Prospective Registry LAANTERN. Congress of Neurological Surgeons 2017 Annual Meeting
4) Chen CC, Rennert R, Khan U, Tatter SB, Field M, Toyota B, Fecci PE, Judy KD, Mohammadi AM, Landazuri P, Sloan AE, Leuthardt EC. Procedural Safety of Stereotactic Laser Ablation (SLA) And Associated Hospital Stay: Outcome from The First Hundred Patient from LAANTERN Prospective Registry. Congress of Neurological Surgeons 2017 Annual Meeting
5) “Lateral Entorhinal Cortex Dysfunction in Preclinical Alzheimer’s Disease” 39th Annual Conference on Neurobiology of Learning and Memory. Alta, Utah 2014
6) Automated Mapping of Cerebral Blood Volume in the Human Hippocampal Formation. McDonnell Meeting on Adult Neurogenesis. Bridging the Gap Between Mouse Models and Human Cognition. Salk Institute. La Jolla, CA. 2014
7) Developing Automated Imaging Tools to Fully Map Dentate Gyrus Cerebral Blood Volume in Humans. McDonnell Meeting on Adult Neurogenesis. Bridging the Gap Between Mouse Models and Human Cognition. Salk Institute. La Jolla, CA. 2013
8) “Imaging the Hippocampal Circuit in Aging and Disease” Taub Retreat. Columbia University Medical Center. New York, New York. 2013
9) The Application of Standardized Image Space to High Throughput Analysis of Cerebral Blood Volume. Konofagou Lab Meeting. Columbia University Medical Center. New York, New York. 2012
Posters:
1) Developing a Canonical Brain Atlas for Mouse fMRI. Khan UA, Provenzano FA, Sabuncu M, Brickman AM, Duff KE,Moreno H, Small SA. Society for Neuroscience. Washington, DC. 2011.
2) Differential Vulnerability of the Dentate Gyrus to Aging as Revealed by Voxel-Based Analysis of fMRI. Khan UA
Book Chapters:
1) Khan U, Solari D, Kassam AB, Cavallo LM. Scott-Brown’s Othorinolaryngology, 9ed: Anterior Cranial Base surgery, Past Present & Future. In Press. 2025
2) Khan U, Plonsker JH, Rennert R, Levy M. Pediatric Skull Base Tumors; IntechOpen. 2021
3) Plonsker JH, Khan U, Rennert R, Levy M. Pediatric Aneurysms; IntechOpen. 2021
4) Khan U, Steinberg JA, Rennert RC, Pannell JS, Cheung V, Khalessi AA. Traumatic Intracranial Aneurysms; Elsevier Press. 2018
5) Khan U, Ciacci JD. Anterior Lumbar Interbody Fusion; Core Techniques in Operative Neurosurgery 2e; Saunders; 2018
6) Khan U, Ciacci JD. Transforaminal Lumbar Interbody Fusion; Core Techniques in Operative Neurosurgery 2e; Saunders; 2018
Teaching Experience:
University of California, San Diego San Diego California 2018-2023
Teaching Fellow: Graduate and Medical School Neuroanatomy
Patents and Grants:
US20190378275A1 (Feb, 2019): Technologies for Diagnosing Neurological or Psychiatric Illnesses. Application: US16/267,067
UC San Diego Clinical and Translational Research Institute (UL1TR001442)
Posters:
1) Developing a Canonical Brain Atlas for Mouse fMRI. Khan UA, Provenzano FA, Sabuncu M, Brickman AM, Duff KE,Moreno H, Small SA. Society for Neuroscience. Washington, DC. 2011.
2) Differential Vulnerability of the Dentate Gyrus to Aging as Revealed by Voxel-Based Analysis of fMRI. Khan UA
Memberships and Accreditations:
- Congress of Neurological Surgeons/American Association of Neurological Surgeons
- Joint Guidelines Review Committee: Early Career Neurosurgeon Member
- North American Skull Base Society
- Society for Neuroscience
Hospital Affiliations:
Scripps Mercy Hospital
4077 Fifth Avenue
San Diego, CA 92103
Pending Credentialing
Scripps Mercy Hospital, Chula Vista
435 H Street
Chula Vista, CA 91910
Pending Credentialing
Sharp Memorial Hospital
7901 Frost Street
San Diego, CA 92123
Pending Credentialing
Sharp Grossmont Hospital
5555 Grossmont Center Drive
La Mesa, CA 91944
Pending Credentialing
Sharp Chula Vista Medical Center
751 Medical Center Court
Pending Credentialing